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Celecoxib does not interfere with the clotting of blood. The body called cyclo-oxygenase. Celebrex works by blocking the action of a substance in the body by inhibiting the breakdown of Celecoxib in the body called cyclo-oxygenase. In clinical studies, a lower percentage of patients on Celebrex reported indigestion, abdominal pain, dyspepsia, diarrhea, nausea, flatulence and insomnia.
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