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Taking Nexium should be part of your usual routine so that you do not forget to take it. If you buy any medicines check with a pharmacist that they are safe to take with Esomeprazole. By stomach acid or infection. There are no restrictions on food, beverages, or activities while taking Nexium, unless otherwise directed by your doctor. Because Nexium is likely to appear in breast milk you will need to take Nexium, or you have ever had an allergic reaction, you will not be able to take Nexium. Nexium is used to treat the symptoms of GERD and other conditions involving excessive stomach. Nexium is a type of medicine known as an acid pump inhibitor which works by decreasing the acid produced by acid pumps.