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Like any antidepressant, not everyone responds or tolerates any given medication. Take Celexa together with a monoamine oxidase inhibitor. Celexa is an antidepressant drug used to treat depression. Celexa causes less drug interactions, you should always let your doctor know what other medications you are taking. Celexa causes less drug interactions, you should always let your doctor know what other medications you are taking. Celexa is the newest antidepressant to be approved by theFDA. It is recommended that Celexa be administered as a single oral dose of 20 mg daily. Citalopram is primarily used to treat depression.