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Esomeprazole is available with a doctor's prescription and is commonly called by its brand name, Nexium. In patients with gastroesophageal reflux disease, Esomeprazole has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors. Our website, all orders are confidential. Nexium decreases the amount of acid backing up into the esophagus and causing reflux symptoms. Use this medication. Use of Esomeprazole in pregnant women has not been appraised. Nexium is used to treat ulcers, gastroesophageal reflux disease, and other conditions involving excessive stomach. Esomeprazole prevents symptoms and damage to the gastrointestinal tract caused by stomach acid or infection.