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Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be noted that it is very different from another group of steroids, called anabolic steroids, which have gained notoriety because of their abuse by some athletes and body builders. Prednisone typically does not produce immediate effects and must be used for several days before the needed effect is achieved. Steroid medication can weaken your immune system, making it easier for you to get an infection. Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Prednisone is inactive in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver. Prednisone, are commonly used to suppress the immune system plays an important role. Prednisone to Prednisolone is impaired.