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For the shortest possible time necessary to relieve your symptoms. Celecoxib does not interfere with the clotting of blood. Celecoxib does not prevent the progression of either type of arthritis. This medication helps you perform more of your normal daily activities. When the benefits outweigh the potential risk to the fetus. Celecoxib does not prevent the progression of either type of arthritis. This medicine. Celecoxib is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. The dose usually is 100 mg twice daily or 200 mg as a single dose.