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Mark noticed: "The balance of certain natural chemicals in the brain. With continued treatment, Paxil can help restore the balance of certain natural chemicals in the brain. Paxil should be taken once a day, either in the morning or evening, with or without food. It convenient to take Paxil and talk to your doctor if you are pregnant or could become pregnant during treatment. This drug must be taken regularly for a few weeks before its full effect is felt. Recent studies suggest an increased risk of Paxil birth defects for pregnant women during their first trimester. Recent studies suggest an increased risk of Paxil birth defects for pregnant women during their first trimester."