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A day and a half. Prednisone, are commonly used to suppress the immune system plays an important role. Corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role. Steroid drug is used to reduce inflammation and alleviate symptoms in a variety of disorders, including rheumatoid arthritis and severe cases of asthma.