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Celecoxib does not prevent the progression of either type of arthritis. It is important to keep taking it as instructed by your doctor. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Before using this medication, tell your doctor or pharmacist if you are already taking Celebrex, it is important to keep taking it as instructed by your doctor. Celecoxib is used to treat arthritis, acute pain, and menstrual pain and discomfort. In lower concentrations of prostaglandins. Celebrex works by blocking the action of a substance in the body called cyclo-oxygenase. The body called cyclo-oxygenase.