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Levaquin is concentration-dependent, meaning it kills bacteria most efficiently when the right amount of medicine has been absorbed into your body. Taking Levofloxacin with an acidic beverage such as a cola drink may increase its absorption. Levaquin is generally well tolerated however skin rashes, nausea, and stomach pain. Given with theophylline, Levofloxacin can increase theophylline blood levels. This class is known as Levaquin. If you have any questions. Be closely monitored.