Side effects of Cephalexin. Keflex is effective antibiotic therapy for skin and skin structure infections and is the most commonly prescribed antibiotic for that reason. Patients with known allergy to the cephalosporin group of antibiotics. Although side effects from Cephalexin are not common, they can occur. The most common side effects of Cephalexin. Cephalexin belongs to a class of antibiotics called cephalosporins.
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